The eyes of the whole world are focused on the vaccine at the moment to prevent corona. However, it is not yet clear how effective it will be against COVID-19. But scientists believe that the effect of the vaccine will depend more on mutations in the genetic structure of the virus. Accordingly, a change in the vaccine may be required. If the virus does not mutate much, then the same vaccine will remain effective on most people.
Many scientists have given two major situations regarding the effects of mutation and vaccine, a special look at them …
Such a vaccine will work on all but
the success of any vaccine is possible only when the virus does not mutate. Scientists say that like other viruses, Kovid-19 is mutating from one person to another. However, the process of infection remains the same. Normally, any virus overcomes the cell and gets involved in the replication. In some cases, mutations may appear in this replication. But mutations take time. Antibodies that were given by the vaccine typically deal with limited mutations.
If the mutation reduces the effect of the vaccine …
If the corona performs a mutation in such a way that the antibody does not affect it, then the same vaccine will not work for everyone. The antibody shows its effect by stopping the virus antigen, but if the virus continues to make changes in the antigen, the effect of the antibody is reduced. This is often seen in flu viruses when the same virus is introduced with many strains. Different strains are required for each strain. Keeping these new strains in mind, scientists make vaccines.
Not much change expected
However, scientists believe that at present people do not have widespread immunity against corona. Therefore, the virus does not need many changes to survive. Even if the size of the antigen changes from the mutation, it will not be very stable. But the day people will be immune against effective strains of the corona, then the chances of its becoming new strains will increase.
Changes in the genome can be seen after the vaccine
One scientist says that Kovid-19 is mutating. Molecular biologist Dr. Peter Thielen at the John Hopkins Applied Physics Laboratory says that 11 types of mutations have so far been found to be common in thousands of samples of patients. But currently, it has only one strain worldwide. There is very little change in its spike protein, so it will not change its form very much. Thielen says that it is not yet clear how Corona’s genome will change after the use of the vaccine. So, we are watching it closely.
